The Opportunity
Esco Lifesciences Group is Singapores most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.
Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in
Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.
Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.
Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.
We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.
The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.
Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.
Esco Aster.
One World Biosolutions for One Health.
Who were looking for
Physical/Mental Requirements/Work Environmen
Ability to read, analyze and interpret scientific data and publications.
Ability to author or review protocols, technical reports and technology transfer documents.
Ability to author or review standard operating procedures and other related documents.
Ability to define problems, collect data, establish facts, and draw conclusions.
Ability to focus.
Repetitive motions due to certain laboratory techniques.
Ability to adapt and keep up with rapid changes in a fluid and dynamic environment as this is a rapidly evolving space
The Scope
Esco Aster develops, produces, and commercializes APIs/Small Molecules, hiPSC, Virus/Viral Vector based solutions. Our offerings range from concept development to pre-clinical studies, including custom manufacturing of a range of cell types, discovery services (disease modelling, drug screening, and safety assays) and manufacturing process development to support cell therapy products as well as cultivated meat.
Interfacing between our chemical and biological teams is our Stemistry department. Identify and unlock mechanisms of action as well as deriving cell models to determine host cell interactions and chemical to cells interactions for the following purpose:
Develop viral sensitizers for increasing yield of our virus/viral vector production.
Increase differentiation of iPSCs into target cell population.
Increase biomass expansion to replace serum/growth factors as used in cultivated meat.
Develop chemistry for affinity chromatography for extracellular vesicles/exosomes.
Develop safety/tox analytics for novel foods.
We are looking for a new team member with proven experience in host to cell interaction. You will be an essential part of our multidisciplinary team of researchers, working both independently but also as part of a larger team.
The ideal candidate has a strong work ethic, a critical mind, and excellent communication skills.
The Associate Scientist will be involved in all aspects of our projects as the interface between our cellular and chemistry department.
Activities include advanced stem cell culture; state of the art differentiation processes and downstream processing.
Report to: Selected candidate will report to CEO and scientist-in-residence
Primary work location: Ayer Rajah, Singapore
Job Responsibilities
Develop and validate cell models to study chemical, biopolymer, peptide to cell and host to cell interaction.
Execute studies to determine and analyze cellular fate.
Perform in process analyses and cell-based assays including multiomics for functional characterization.
Support routine lab activities such as stock management and equipment maintenance
Collect and record data accurately following standard operation procedures in compliance with Quality Management System
Pro-active mindset, propose solutions and participate in investigations whenever needed.
Requirements
PhD in Life Sciences/Chemistry or related disciplines.
Minimum 5 years relevant work experience.
Experience with cell culture and the ability to adapt for cross functional work involving cell culture and evaluation of the impact of small molecule in cell culture.
Ability to plan and perform experiments in an interdisciplinary environment, both independently and efficiently.
Familiarity with good laboratory practices (GLP);
Proven track record in experimental design, SOP development, review and writing, data and statistical analysis.
Ability to write scientific publications and present data at national and international conferences.
Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
Excellent written and verbal communication skills.
Able to work independently, self-starter, self-motivated and task oriented.
Strong team player, develop positive relationship with a strong set of interpersonal skills.
During the start-up phase of the team/facility, be willing to take on expanded role to set up workflow/processes as needed.
Apply now by submitting a Cover Letter and CV to [Confidential Information].
